Recombinant CX3CR1 antibody (AA 300-350)

Catalog No. ABIN7795801

This anti-CX3CR1 antibody is a Rabbit Monoclonal antibody detecting CX3CR1 in IHC. Suitable for Human.

Quick Overview for Recombinant CX3CR1 antibody (AA 300-350) (ABIN7795801)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BLR362N

Product Details anti-CX3CR1 Antibody

Binding Specificity: AA 300-350

Purpose: Rabbit anti-CX3CR1 Recombinant Monoclonal Antibody [BLR362N]

Purification: Purified

Immunogen: between 300 and 350

Isotype: IgG

Application Details

Application Notes: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1

Background: CX3CR1 is a receptor for the C-X3-C chemokine fractalkine (CX3CL1) which is present on many early leukocyte cells. Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1 is also a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. [taken from NCBI Entrez Gene (Gene ID: 1524)].

Gene ID: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin